The Padres ruled the Bronx with TRUENOS de Soto and Tatis Jr.

NEW YORK — Juan Soto and Fernando Tadis Jr. each hit two-run home runs, and both stayed at home plate to send the ball flying into the second floor of the stands in Friday’s game against the San Diego Padres. They beat the New York Yankees. 5-1.

San Diego, after a stuttering start to the season, took the opener of the series between the teams with expensive payrolls.

Soto gave the Padres the lead in the fifth inning against 24-year-old right-hander Randy Vasquez (0-1), making his major league debut. Tatis extended his lead to 4-0 in the sixth against Ron Marinaccio.

Shots totaled 871 feet.

Joe Musgrove (2-2) pitched in New York for the first time since going seven scoreless innings to defeat the Mets in last year’s wild-card series clincher.

He allowed one run and six hits in 6 1/3 innings, striking out six and walking no.

Anthony Rizzo hit an RBI grounder in the sixth for the Yankees after Kleyber Torres’ single and Aaron Judge’s double.

For the Padres, Dominican Tadis went 5-1 with one run scored and two RBIs, while Soto went 5-2 with two runs scored and two RBIs. Venezuela won the 4-1 RBI with an RBI.

For the Yankees, Venezuela Torres scored a run to make it 4-1.