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New teeth? Science found a way to REGENERATE teeth

Rudyard Kipling by Rudyard Kipling
April 13, 2021
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Teeth Not only are they an important part of our eating process, as well as helping us digest food, they are an essential factor in our physical appearance.

Many people tend to have complexes because of their teeth, since after the years it begins to deteriorate, and in many cases need dental intervention, and eventually they opt for false teeth, because either the original teeth do not have composure or, because teeth are no longer reborn. At least that was thought until now …

Photo: Instagram @marianardz

Now scientists in Japan have made a discovery that may make it possible for teeth grow back. They found, with animal studies, that deletion of the USAG-1 gene through the use of its antibody can efficiently lead to tooth growth.

How do new teeth appear?

This is a new study by scientists from the Kyoto University and the Fukui University that may offer some hope. The team reports that an antibody to a gene, the gen-1 or USAG-1 associated with sensitization, it can stimulate tooth growth in mice with dental agenesis, a oral affection.

Although the normal adult mouth has 32 teeth, approximately 1% of the population has more or less due to congenital conditions. Scientists have explored the genetic causes of cases with too many teeth as clues to tooth regeneration in adults.

So can my teeth regenerate or not?

According to Katsu Takahashi, one of the study’s lead authors, the fundamental molecules responsible for tooth development have already been identified. The scientists found that the growth of multiple organs and tissues is modulated long before the human body is the size of a raisin. Consequently, medications that directly affect its activity are commonly avoided, as the side effects could affect the entire body.

See also  GISAID: One million genomes and counting | Science

Therefore, the scientists investigated the effects of various monoclonal antibodies to USAG-1. Monoclonal antibodies are commonly used to treat cancers, arthritis, and vaccine development. USAG-1 interacts with other chemical compounds and as a result, several of the antibodies led to poor survival and birth rates of the mice, confirming their importance in the growth of the whole body.

Sample of tooth regeneration in a mouse. Photo: Kyoto University

With media information

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Rudyard Kipling

Rudyard Kipling

"Reader. Evil problem solver. Typical analyst. Unapologetic internet ninja."

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